Appearance: white crystalline powder
Specific rotation[a]D20: +22.0~+24.0°(C=1,AcOH)
Melting point: 81-83℃
Boc-D-Ala-OH; Boc-D-alanine 7764-95-6 is the boc protection form of D-Alanine. D-alanine is produced in bacteria, but not eukariotic cells. D-Alalnine forms an important part of a peptide contained in the basal structure of many bacterial cell walls. The antibiotic vancomycin selectively binds D-Ala-D-Ala of membrane peptides.
The susceptibility of S. aurens to cationic antimicrobial peptides is reduced when the C2 positin on the glycerol phosphate of lipoteichoic acid is functioalized with D-alanine.
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