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Structure

1-Boc-piperazine 57260-71-6

1-Boc-piperazine 57260-71-6

Specifications

  • Catalogue No.: 10469
  • Product Name: 1-Boc-piperazine
  • Synonyms: tert-Butyl piperazine-1-carboxylate
  • CAS: 57260-71-6
  • MDL: MFCD00075265
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  • Price: $1300/5kg
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Properties

Assay: 98%
Appearance: white crystalline powder
Mp: 43-47℃
Water content: 0.5% max

1-Boc-piperazine 57260-71-6 is used in Buchwald-Hartwig coupling reaction. 1-Boc-piperazine is an N-Boc protected piperazine. Crosscoupling of 1-Boc-piperazine with aryl iodides using CuBr/1,1′-bi-2-naphthol (catalyst) and K3PO4 (base) has been reported. 1-Boc-piperazine undergoes Buchwald-Hartwig coupling reactions with aryl halides. 1-Boc-piperazine can be prepared in 80% yield via solvent-free N-Boc protection catalyzed by iodine.

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