α-ketoglutaric acid: 45.5±1.0%
Appearance: white crystalline powder
Specific rotation[a]D20: +14.5±1.0°
Heavy metal(Pb): 10ppm max
Arsenic: 1ppm max
Loss on drying: 0.50% max
Ignition residue: 0.10% max
Arginine alpha-ketoglutarate 16856-18-1 is a salt of the amino acid arginine and alpha-ketoglutaric acid. It is marketed as a bodybuilding supplement. The components are intermediates in the metabolism of nitric oxides, but no reputable scientific evidence shows any benefits from taking AAKG as a dietary supplement.
A recent study examined the effects of AAKG supplementation on heart rate, blood pressure, blood flow, NOx/NO2 levels, and L-arginine levels. Minimal observed changes were attributed to resistance exercise used in the experimental design, not to AAKG supplementation, although arginine levels were found to have been elevated.
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